Force-generating mechanisms of anaphase in human cells

Molecular Mechanisms of Luteolin Induced Growth Inhibition and Apoptosis of Human Osteosarcoma Cells

Luteolin is a flavone in medicinal plants as well as some vegetables and spices. It is a natural anti-oxidant with less pro-oxidant potential but apparently with a better safety profile. The purpose of this study was to investigate the molecular mechanism of luteolin-mediated apoptosis of MG-63 human osteosarcoma cells. MTT assay kit was employed to evaluate the effects of luteolin on MG-63 cel...

Molecular Mechanisms of Luteolin Induced Growth Inhibition and Apoptosis of Human Osteosarcoma Cells

Luteolin is a flavone in medicinal plants as well as some vegetables and spices. It is a natural anti-oxidant with less pro-oxidant potential but apparently with a better safety profile. The purpose of this study was to investigate the molecular mechanism of luteolin-mediated apoptosis of MG-63 human osteosarcoma cells. MTT assay kit was employed to evaluate the effects of luteolin on MG-63 cel...

The Force Generating Components

Dealing with mechanics: mechanisms of force transduction in cells.

Physical cues, such as forces applied to a cell membrane or the stiffness of materials to which cells adhere, are increasingly recognized as essential determinants of biological function, and mechanical stimuli can be as important as chemical stimuli in determining tissue fate or contributing to pathological states. The physical environment of the cell can act in concert with, or sometimes over...

Electrostatic force in prometaphase, metaphase, and anaphase-A chromosome motions.

Primitive cells had to divide using very few biological mechanisms. This work proposes physicochemical mechanisms, based upon nanoscale electrostatics, which explain and unify the motions of chromosomes during prometaphase, metaphase, and anaphase A. In the cytoplasmic medium that exists in biological cells, electrostatic fields are subject to strong attenuation by ionic screening, and therefor...